Registration Dossier
Registration Dossier
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EC number: 204-635-6 | CAS number: 123-56-8
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- NIOSH Exchange Chemicals. Vol. NX#03763
- Author:
- U.S. Army Armament Research & Development Command, Chemical Systems Laboratory
- Reference Type:
- secondary source
- Title:
- Succinimide
- Author:
- EPA
- Year:
- 2 011
- Bibliographic source:
- ACToR:Aggregated Computational Toxicology Resource; http://actor.epa.gov/actor/faces/GenericChemical.jsp
Materials and methods
Test guideline
- Guideline:
- other: no data
- Principles of method if other than guideline:
- Acute intravenous toxicity study in mice
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Succinimid
- IUPAC Name:
- Succinimid
- Details on test material:
- - Name: Succinimid (German)
- Amount: 50 g
- Storage of the test substance: 4°C
Constituent 1
- Specific details on test material used for the study:
- not specified
Test animals
- Species:
- mouse
- Strain:
- not specified
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- not specified
Administration / exposure
- Route of administration:
- unspecified
- Vehicle:
- not specified
- Details on exposure:
- not specified
- Doses:
- not specified
- No. of animals per sex per dose:
- not specified
- Control animals:
- not specified
- Details on study design:
- not specified
- Statistics:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 320 mg/kg bw
- Based on:
- not specified
- Mortality:
- not specified
- Clinical signs:
- not specified
- Body weight:
- not specified
- Gross pathology:
- not specified
- Other findings:
- not specified
Applicant's summary and conclusion
- Conclusions:
- In an acute oral toxicity in mice, an LD50 value of 320 mg/kg bw was determined.
- Executive summary:
In an acute oral toxicity in mice, an LD50 value of 320 mg/kg bw was determined.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
