Registration Dossier

Administrative data

Endpoint:
relative self-ignition temperature (solids)
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because the substance is a solid having a melting point <= 160°C
Justification for type of information:
The melting point of the substance is very close to the cut-off for data waiving (177.4°C).
During the melting point study, the temperature was raised up to 372°C. During this study, decomposition and/or reaction of the substance occurred and a brown molten residue remained. No ignition of the substance was observed.
Additionally, the self-heating study performed at temperatures up to 140°C showed no self-ignition of the substance.
Therefore, the substance is considered to have no self-ignition temperature.
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Reason / purpose:
data waiving: supporting information
Reference
Endpoint:
self-heating substances / mixtures
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2019
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
UN Manual of Tests and Criteria: Test N.4 (Test method for self-heating substances)
Version / remarks:
2015
Deviations:
no
GLP compliance:
yes
Test procedure:
100 mm sample cube at 140°C
Max. temp. reached:
140
Induction time (h):
24
Result:
negative outcome (no effect observed)
Interpretation of results:
GHS criteria not met
Conclusions:
Self-heating of CH02672 was determined in accordance with UN Test N.4 “Test Method for Self-heating Substances”.
From the negative result obtained at 140°C using a 10 cm sample cube, it was concluded that CH02672 is not a self-heating substance.
Reason / purpose:
data waiving: supporting information
Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2019
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Version / remarks:
July 27, 1995
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Version / remarks:
March 04, 2016
Deviations:
no
Qualifier:
according to
Guideline:
EPA OPPTS 830.7200 (Melting Point / Melting Range)
Version / remarks:
March 1998
Deviations:
no
GLP compliance:
yes
Type of method:
differential scanning calorimetry
Key result
Melting / freezing pt.:
177.4 °C
Decomposition:
yes
Decomp. temp.:
275 °C
Conclusions:
The melting point of CH02672 was 177.4°C, as determined using differential scanning calorimetry (OECD 102).

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion