Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 265-332-2 | CAS number: 65059-42-9
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation / corrosion, other
- Remarks:
- aaa
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2019.04.05~2019.05.21
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 019
- Report date:
- 2019
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
- Version / remarks:
- Adopted : 28 July 2015
- GLP compliance:
- yes
Test material
- Reference substance name:
- Trimethyloctylammonium methyl sulphate
- EC Number:
- 265-332-2
- EC Name:
- Trimethyloctylammonium methyl sulphate
- Cas Number:
- 65059-42-9
- Molecular formula:
- C11H26N.CH3O4S
- IUPAC Name:
- trimethyl(octyl)azanium methyl sulfate
- Test material form:
- solid: bulk
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- New Zealand White
- Remarks:
- Yac:NZW(KBL), Rabbit, SPF
Test system
- Observation period:
- 72h
- Number of animals:
- 3 males (Initial test : 1 head, Confirmatory test : 2 head)
Results and discussion
In vivo
Resultsopen allclose all
- Irritation parameter:
- erythema score
- Basis:
- animal #1
- Time point:
- 24/48/72 h
- Score:
- > 0 - <= 1
- Max. score:
- 1
- Remarks on result:
- probability of weak irritation
- Irritation parameter:
- edema score
- Basis:
- animal #2
- Time point:
- 24/48/72 h
- Score:
- > 0 - <= 1
- Max. score:
- 1
- Remarks on result:
- probability of weak irritation
Applicant's summary and conclusion
- Interpretation of results:
- study cannot be used for classification
- Conclusions:
- As a result of acute dermal irritation and corrosion test in rabbit, Trimethyloctylammonium
methyl sulphate was caused weak skin reactions but was not considered to be
classified as Hazard Class according to Globally Harmonized System of Classification
and Labelling of Chemicals (GHS).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
