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Physical & Chemical properties

Vapour pressure

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Administrative data

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
from 2018-08-15 to 2018-09-05
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7950 (Vapor Pressure)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: Knudsen cell
Key result
Temp.:
20 °C
Vapour pressure:
214.2 Pa
Temp.:
25 °C
Vapour pressure:
380 Pa
Temp.:
50 °C
Vapour pressure:
5 115 Pa

The vapour pressure was measured in the temperature range of 27 to 42 °C. For the evaluation the vapour pressure values in the range of 27 to 42 °C were used.

Table 1. Results of the Effusion method

Stage No.

Temperature, °C

Δm/Δt, mg/min

Vapour pressure, Pa

1

26.9

1.8577

4.7596 x 1E+2

2

30.0

2.4632

6.3435 x 1E+2

3

33.0

3.5810

9.2677 x 1E+2

4

36.0

4.9791

1.2949 x 1E+3

5

39.0

6.6363

1.7342 x 1E+3

6

42.0

8.6756

2.2781 x 1E+3

 

Conclusions:
The vapour pressure of the test item was determined at 20, 25 and 50 °C to be 214.2 Pa, 380 Pa and 5115 Pa, respectively.
Executive summary:

A study was conducted according to OECD TG 104, Regulation (EC) No 440/2008 method A.4 and OPPTS 830.7950 to determine the vapour pressure of the test item. The vapour pressure of the test item was determined at temperatures between 27 and 42 °C using the effusion method (Knudsen cell). For the evaluation the vapour pressure values in the range of 27 to 42 °C were used. The vapour pressure of the test item was calculated by extrapolation of the measured vapour pressure curve for the temperatures 20, 25 and 50 °C. The vapour pressure was calculated to be 214.1 Pa at 20 °C, 380 Pa at 25 °C and 5115 Pa at 50 °C, respectively.

Description of key information

The vapour pressure of the test item was determined at 20, 25 and 50 °C to be 214.2 Pa, 380 Pa and 5115 Pa, respectively.

Key value for chemical safety assessment

Vapour pressure:
214.2 Pa
at the temperature of:
20 °C

Additional information

A study was conducted according to OECD TG 104, Regulation (EC) No 440/2008 method A.4 and OPPTS 830.7950 to determine the vapour pressure of the test item. The vapour pressure of the test item was determined at temperatures between 27 and 42 °C using the effusion method (Knudsen cell). For the evaluation the vapour pressure values in the range of 27 to 42 °C were used. The vapour pressure of the test item was calculated by extrapolation of the measured vapour pressure curve for the temperatures 20, 25 and 50 °C. The vapour pressure was calculated to be 214.1 Pa at 20 °C, 380 Pa at 25 °C and 5115 Pa at 50 °C, respectively.