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Registration Dossier
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EC number: 606-373-1 | CAS number: 197706-50-6
Auto flammability
Administrative data
- Endpoint:
- auto-ignition temperature (liquids)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2017-01-31 to 2017-06-06
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.15 (Auto-Ignition Temperature (Liquids and Gases))
- Deviations:
- no
- GLP compliance:
- yes
Test material
- Reference substance name:
- (-)-[R-(R*,R*)]-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran
- EC Number:
- 606-373-1
- Cas Number:
- 197706-50-6
- Molecular formula:
- C11H11FO2
- IUPAC Name:
- (-)-[R-(R*,R*)]-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran
- Test material form:
- liquid: viscous
- Details on test material:
- - Physical state: Viscous liquid
- Appearance: Yellow to orange, clear liquid
Constituent 1
- Specific details on test material used for the study:
- - Batch n°: I16HB3200
- Analytical purity: 83.7%
- Expiration date: 2017-07-25
- Storage condition: at room temperature
Results and discussion
Auto-ignition temperature (liquids / gases)
- Auto-ignition temperature:
- 405 °C
- Atm. press.:
- >= 1 027.7 - <= 1 028.7 hPa
Any other information on results incl. tables
Ignition of the test item within 5 minutes after introduction was observed with each sample volume and with each test a minimum auto-ignition temperature was obtained. The maximum deviation between the three values was < 20°C. According to the guidelines, no further testing was required.
The lowest temperature at which ignition of the test item occurred was 406°C. This temperature was rounded down to the nearest multiple of 5°C giving an auto-ignition temperature of the test item of 405°C.
Applicant's summary and conclusion
- Conclusions:
- Commercially available auto-ignition temperature apparatus was used for the determination of the degree of auto-ignitability of JNJ-17337008-AAA (T001591).
The test item is auto-ignitable with an auto-ignition temperature of 405°C at 1027.7 -1028.7 hPa.
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