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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

There is no data available for this substance. However, key and supporting data is available for structural analogues. The data is read across to this substance based on analogue read across and a discussion and report on the read across strategy is provided as an attachment in IUCLID Section 13.

There was no experimental data available for this sustance or structural analogues for long-term toxicity to fish, long-term toxicity to aquatic invertebrates, and toxicity to microorganisms. For these endpoints, the aquatic toxicity was estimated using the PETROTOX computer model (v4.0), which combines a partitioning model used to calculate the aqueous concentration of hydrocarbon components as a function of substance loading with the Target Lipid Model used to calculate acute and chronic toxicity of nonpolar narcotic chemicals. PETROTOX computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a hydrocarbon substance and membrane-water partitioning coefficients (KMW) that describe the partitioning of the hydrocarbons between the water and organism.

According to the harmonised CLP legislation (2008), Annex VI, this substance is classified for the environment as aquatic chronic category 2 with the hazard statement H411: Toxic to aquatic life with long lasting effects.

Additional information

Key and supporting information is summarised below:

Short-term toxicity to fish

Hydrocarbons, C6-C7, isoalkanes, cyclics, <5% n-hexane presented a 96-h LL50 (mortality) for Oncorhynchus mykiss of 12 mg/L.

Hexane presented a 48-h LC50 (mortality) for Oryzias latipes of >1000 µg/mL (>1000 mg/L).

Long-term toxicity to fish

The aquatic toxicity was estimated using the PETROTOX computer model (v4.0), which combines a partitioning model used to calculate the aqueous concentration of hydrocarbon components as a function of substance loading with the Target Lipid Model used to calculate acute and chronic toxicity of nonpolar narcotic chemicals. PETROTOX computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a hydrocarbon substance and membrane-water partitioning coefficients (KMW) that describe the partitioning of the hydrocarbons between the water and organism.

Short-term toxicity to aquatic invertebrates

Hydrocarbons, C6-C7, isoalkanes, cyclics, <5% n-hexane presented a 48-h EL50 (mobility) for Daphnia magna of 3.0 mg/L (WAF).

Hexane presented a 48-h LC50 (mortality) for Daphnia magna of 45 mmol/m3(WAF).

Long-term toxicity to aquatic invertebrates

The aquatic toxicity was estimated using the PETROTOX computer model (v4.0), which combines a partitioning model used to calculate the aqueous concentration of hydrocarbon components as a function of substance loading with the Target Lipid Model used to calculate acute and chronic toxicity of nonpolar narcotic chemicals. PETROTOX computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a hydrocarbon substance and membrane-water partitioning coefficients (KMW) that describe the partitioning of the hydrocarbons between the water and organism.

Toxicity to algae and cyanobacteria

Hydrocarbons, C6-C7, isoalkanes, cyclics, <5% n-hexane presented a 72-h ErL50 of 55 mg/L, a 72-h EbL50 of 26 mg/L and a 72-h NOEL of 30 mg/L for Raphidocelis subcapitata based on growth rate.

Hexane presented a 10-d EC50 (growth rate) for Chlorella pyrenoidosa of 2.66% v/v of test substance.

Toxicity to microorganisms

The aquatic toxicity was estimated using the PETROTOX computer model (v4.0), which combines a partitioning model used to calculate the aqueous concentration of hydrocarbon components as a function of substance loading with the Target Lipid Model used to calculate acute and chronic toxicity of nonpolar narcotic chemicals. PETROTOX computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a hydrocarbon substance and membrane-water partitioning coefficients (KMW) that describe the partitioning of the hydrocarbons between the water and organism.