Registration Dossier

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Sep 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2019
Report Date:
2019

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
no
Type of method:
flask method

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Water solubility
Key result
Water solubility:
0.907 g/L
Temp.:
25 °C
pH:
ca. 6

Any other information on results incl. tables

 Preliminary test

The water solubility of the test substance was 0.908 g/L.

 

Definitive test

The concentration of the test substance in the test samples is given in the following table.

 

Sample
number

Time shaken
at ca. 30 °C

(hours)

Time equilibrated at 25 °C

(hour)

Concentration

 

(g/L)

pH

1

24

24

0.939

6.0

2

48

24

0.926

5.9

3

72

24

0.928

5.9

4

96

24

0.907

5.9

5

120

24

0.906

6.0

6

144

24

0.907

6.0

 

The mean concentration of the test substance in the 96, 120, 144 hour the test sample was 0.907 g/L.

 

Conclusion

The water solubility of the test item has been determined to be 0.907 g/L at 25.0 ± 0.5 °C.

Applicant's summary and conclusion

Conclusions:
The water solubility of the substance has been determined to be 0.907 g/L at 25 °C (pH ca. 6)