Registration Dossier
Registration Dossier
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EC number: 946-354-8 | CAS number: -
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- other: read-across from constituent CrIII
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- publication
- Title:
- Inorganic chromium(III) compounds
- Author:
- WHO
- Year:
- 2 009
- Bibliographic source:
- Concise international chemical assessment document 76, International Programme on Chemical Safety (IPCS)
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 405 (Acute Eye Irritation / Corrosion)
Test material
- Reference substance name:
- Chromium (III) oxide
- EC Number:
- 215-160-9
- EC Name:
- Chromium (III) oxide
- Cas Number:
- 1308-38-9
- Molecular formula:
- Cr2O3
1
Test animals / tissue source
- Species:
- rabbit
- Strain:
- not specified
Test system
- Vehicle:
- not specified
Results and discussion
In vivo
Results
- Remarks on result:
- no indication of irritation
- Other effects:
- No reactions meeting the criteria for eye irritancy were observed.
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- No reactions meeting the criteria for eye irritancy were observed.
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