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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Data investigating the aquatic toxicity ofFatty acids, C8-10-(even numbered), esters with pentaerythritol and adipic acid (EC 948-383-1)are not available. Therefore, a read-across to structurally related substances with similar ecotoxicological profiles was conducted for the following endpoints: Short-term toxicity to fish, Short- and Long-term toxicity to aquatic invertebrates, Toxicity to aquatic algae and cyanobacteria and Toxicity to microorganisms. Based on the high degree of similarity between the structural and physico-chemical properties of the target and source substances, the source substances are considered suitable representatives for the assessment of the aquatic toxicity of the target substance. A detailed analogue approach justification is provided in the technical dossier (please refer to IUCLID Section 13).

For the endpoint short-term toxicity to fish, aread-across to the structurally and chemically closely related source substance Fatty acids, C8-10, mixed esters with adipic acid and trimethylolpropane (CAS 95912-89-3) and Decanoic acid, mixed esters with heptanoic acid, octanoic acid, pentaerythritol and valeric acid (CAS 71010-76-9)was conducted. Acute toxicity of the source substances to fish was not observed. The lowestLC50 (96 h) was determined as > 0.704 mg/L (arithmetic mean measured concentration).Based on the available results from this read-across, it can be concluded thatFatty acids, C8-10-(even numbered), esters with pentaerythritol and adipic acid (EC 948-383-1)shows no acute toxicity to fish up to the limit of saturation (< 165 µg/L at 20 °C, pH 6.3; OECD Guideline 105, column elution method).

For the endpoint short-term toxicity to aquatic invertebrates, a read-across to the structurally related source substancesFatty acids, C8-10, mixed esters with adipic acid and trimethylolpropane (CAS 95912-89-3) and Decanoic acid, mixed esters with heptanoic acid, octanoic acid, pentaerythritol and valeric acid (CAS 71010-76-9)was conducted. The lowest measured EL50 (48h) was determined to be > 100 mg/L (nominal). Based on the available results from this read-across, it can be concluded thatFatty acids, C8-10-(even numbered), esters with pentaerythritol and adipic acid (EC 948-383-1)shows no acute toxicity to aquatic invertebrates up to the limit of water solubility (< 165 µg/L at 20 °C, pH 6.3; OECD Guideline 105, column elution method).

For the endpoint long-term toxicity to aquatic invertebrates, a read-across to the structurally related source substancesFatty acids, C8-10, mixed esters with adipic acid and trimethylolpropane (CAS 95912-89-3) and Decanoic acid, mixed esters with heptanoic acid, octanoic acid, pentaerythritol and valeric acid (CAS 71010-76-9) was conducted. The lowest NOEC (21 d) was determined as1 mg/L (WAF)(immobility, reproduction). Based on the available results from this read-across, it can be concluded thatFatty acids, C8-10-(even numbered), esters with pentaerythritol and adipic acid (EC 948-383-1)shows no long-term toxicity to aquatic invertebrates up to the limit of water solubility (< 165 µg/L at 20 °C, pH 6.3; OECD Guideline 105, column elution method).

For the endpoint Toxicity to aquatic algae and cyanobacteria, a read-across to the structurally related source substanceDecanoic acid, mixed esters with heptanoic acid, octanoic acid, pentaerythritol and valeric acid (CAS 71010-76-9)was conducted. TheEL50 (72 h) was determined as > 100 mg/L and the NOELR (72 h) as100 mg/L. Based on the available results from this read-across, it can be concluded thatFatty acids, C8-10-(even numbered), esters with pentaerythritol and adipic acid (EC 948-383-1) shows no toxicity to aquatic algae up to the limit of water solubility (< 165 µg/L at 20 °C, pH 6.3; OECD Guideline 105, column elution method).

For the endpoint Toxicity to microorganisms, a read-across to the structurally related source substanceDecanoic acid, mixed esters with heptanoic acid, octanoic acid, pentaerythritol and valeric acid (CAS 71010-76-9)was conducted. AnEC50 > 1000 mg/L (nominal) and EC10 > 1000 mg/L (nominal) were determined.Based on the available results from this read-across, it can be concluded thatFatty acids, C8-10-(even numbered), esters with pentaerythritol and adipic acid (EC 948-383-1) is non-inhibitory of aquatic microorganisms activity.

Based on the study results from available source substances, it can be concluded thatFatty acids, C8-10-(even numbered), esters with pentaerythritol and adipic acid (EC 948-383-1)is not toxic to freshwater organisms up to the limit of the water solubility (< 165 µg/L at 20 °C, pH 6.3; OECD Guideline 105, column elution method).