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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
GLP compliance:
yes
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
ca. 7.7
Temp.:
25 °C
Remarks on result:
other: the PH value was not available
Details on results:
The linear equation is available because of the coefficient of correlation is r = 0.9627>0.90. Two independent determination results from the injections of the sample solution, are 7.70 and 7.70; the deviation is less than 0.1. This proved that the determination results are available and the average value, 7.7 can be as the final data of logPow of the target analyte.

mean value of 2 measurements

Conclusions:
The partition coefficient of test substance was determined to be 7.7 at 25 °C
Executive summary:

In this guideline (OECD 117 "Partition Coefficient (n-octanol/water), HPLC method") study, the n-octanol/water partition coefficient of the test material (EC254-935-6) was determined to be Log Pow 7.7 at 25 ºC.

Description of key information

Study carried out according to guideline.

Key value for chemical safety assessment

Log Kow (Log Pow):
7.7
at the temperature of:
25 °C

Additional information

The measurement was carried out using HPLC method.