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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 947-972-0 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Short-term toxicity to aquatic invertebrates
The short-term toxicity of Thio Isocyanate Adduct to the freshwater aquatic invertebrate, Daphnia magna, was assessed via an OECD Guideline 202 (‘Daphnia sp. Acute Immobilisation Test’) study. The study was performed at a GLP accredited laboratory, fulfilled the validity criteria described by the guideline and is well documented and is therefore considered to be reliable.
Exposures of D. magna to the test item showed that the 48 hour EC50 was beyond the considered maximum soluble concentration of the test item (i.e.exceeded an average exposure concentration of 0.0062 mg/L for the first constituent and of 5.1 mg/L for the second constituent).
Toxicity to aquatic algae and cyanobacteria
The toxicity of Thio Isocyanate Adduct to the freshwater algae, Pseudokirchneriella subcapitata, was assessed via an OECD Guideline 201 (‘Freshwater Alga and Cyanobacteria, Growth Inhibition Test’) study. The study was performed at a GLP accredited laboratory, fulfilled the validity criteria described by the guideline and is well documented and is therefore considered to be reliable.
Exposures of P. subcapitata to the test item resulted in Time Weighted Average (TWA) measured 72 hour EL50 values of >100 mg/L for both growth rate inhibition and yield. The 72 hour EC50 based on the first constituent was >0.20 µg/L for both growth rate inhibition and yield. The 72 hour EC50 based on the second constituent was 59 µg/L for both growth rate inhibition and yield. The resulting 72 hour NOELR values for growth rate inhibition and yield were 32 mg/L based on statistical significance and 100 mg/L based on biological relevance. The resulting 72 hour NOEC values based on the first constituent for growth rate inhibition and yield was 0.054 µg/L based on statistical significance and 0.20 µg/L based on biological relevance. The resulting 72 hour NOEC values based on the first constituent for growth rate inhibition and yield was 11 µg/L based on statistical significance and 59 µg/L based on biological relevance.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.