Registration Dossier
Registration Dossier
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EC number: 205-305-4 | CAS number: 137-66-6
Particle size distribution (Granulometry)
Administrative data
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods with acceptable restrictions
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 2 015
- Report date:
- 2015
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- High speed image analysis
- GLP compliance:
- no
- Type of method:
- other: Image analysis
- Remarks:
- Sympatec QICPIC (0179 Q) & RODOS (injection disperser)
Test material
- Reference substance name:
- 6-O-palmitoylascorbic acid
- EC Number:
- 205-305-4
- EC Name:
- 6-O-palmitoylascorbic acid
- Cas Number:
- 137-66-6
- Molecular formula:
- C22H38O7
- IUPAC Name:
- 6-O-palmitoylascorbic acid
- Test material form:
- solid: particulate/powder
Constituent 1
Results and discussion
- Mass median aerodynamic diameter:
- ca. 153 µm
- Geometric standard deviation:
- ca. 26
Particle sizeopen allclose all
- Percentile:
- D10
- Mean:
- ca. 22.9 µm
- St. dev.:
- 3.27
- Key result
- Percentile:
- D50
- Mean:
- ca. 152.79 µm
- St. dev.:
- 25.62
- Percentile:
- D90
- Mean:
- ca. 785.22 µm
- St. dev.:
- 376.04
Applicant's summary and conclusion
- Conclusions:
- The median diameter of the test substance particles was determined to be 153 µm.
- Executive summary:
The following particle size distribution was determined for ascorbyl palmitate:
x10 = 23 µm
x50 = 153 µm (Median value)
x90 = 785 µm
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