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Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Endpoint:
activated sludge respiration inhibition testing
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference
Reference Type:
publication
Title:
Evaluation of the OECD "Activated Sludge Respiration Inhibition Test" for Assessment of the Potential Impact of Chemicals on Wastewater Treatment Systems
Author:
Klecka, G.M. et al.
Year:
1984
Bibliographic source:
NTIS/OTS 0513178 # 86870000228, US Department of Commerce, Springfield, VA, 1-42

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test organisms

Test organisms (species):
activated sludge, domestic

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
3 h

Test conditions

Reference substance (positive control):
yes
Remarks:
3,5-dichlorophenol

Results and discussion

Effect concentrations
Key result
Duration:
3 h
Dose descriptor:
IC50
Effect conc.:
> 1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
inhibition of total respiration
Remarks:
respiration rate

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
IC50 (3h) of the test substance was > 1000 mg/L.