Registration Dossier
Registration Dossier
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EC number: 664-492-4 | CAS number: 742087-49-6
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 004
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: 48 Hours Patch Test
- Deviations:
- not specified
- Principles of method if other than guideline:
- Determination by epidermal contact the primary irritation potential of a test material
- GLP compliance:
- no
Test material
- Reference substance name:
- D-Glucopyranose, oligomeric, C10-16-alkyl glycosides, 2-hydroxy-3-sulfopropyl ethers, sodium salts
- EC Number:
- 664-492-4
- Cas Number:
- 742087-49-6
- Molecular formula:
- (C6O6H3R1)nC3O4SHNa
- IUPAC Name:
- D-Glucopyranose, oligomeric, C10-16-alkyl glycosides, 2-hydroxy-3-sulfopropyl ethers, sodium salts
Constituent 1
Test animals
- Species:
- human
- Strain:
- other: male / female
Test system
- Type of coverage:
- semiocclusive
- Vehicle:
- water
- Remarks:
- 10% dilution in distillated water
- Controls:
- yes
- Duration of treatment / exposure:
- 48 hours
- Observation period:
- 48 hours and 72 hours
- Number of animals:
- 53 subjects
Results and discussion
In vivo
Results
- Irritation parameter:
- erythema score
- Basis:
- mean
- Remarks:
- 53 human subjects
- Time point:
- other: 48/72 hr
- Score:
- 0
- Max. score:
- 0
- Reversibility:
- other: no data
- Remarks:
- no effect seen so no reversibility required
- Remarks on result:
- no indication of irritation
Applicant's summary and conclusion
- Interpretation of results:
- not irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: expert judgment
- Conclusions:
- No visible skin reaction.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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