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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
Deviations:
yes
Remarks:
The following deviation from the study plan occurred: At the time of signing the study plan, the only available test item information was the identification CYANOBICYCLE. Additional test item information was subsequently provided, however, a study plan am
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile
EC Number:
609-091-7
Cas Number:
35202-54-1
Molecular formula:
C11H11NO2
IUPAC Name:
3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile

Results and discussion

Effect concentrations
Key result
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
> 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat. (dissolved fraction)
Basis for effect:
mobility
Remarks on result:
other: Analysis of the test preparations at 0 and 48 hours showed measured test concentrations to range from 99% to 101% of nominal and so the results are based on nominal test concentrations only.

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
Analysis of the test preparations at 0 and 48 hours showed measured test concentrations to range from 99% to 101% of nominal and so the results are based on nominal test concentrations only.
Exposure of Daphnia magna to the test item gave EC50 values based on the nominal test concentration of greater than 100 mg/L. The No Observed Effect Concentration was 100 mg/L.