Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 433-470-4 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
Setafix 1077 induced no visible effects in zebrafish exposed to a filtrate prepared at a loading rate of 100 mg/L. This suggested that LC50 of the test substance were above this concentration level. Due to its soluble limit, the average exposure concentration of Z1077 was measured to be 0.994 mg/L.
Due to the low water solubility, it was reasonable to infer that in natural conditions the test substance would not reach concentration levels toxic to fish.
Setafix X 11342 induced no visible effects in carp exposed to a filtrate prepared at a loading rate of 100 mg/L. The average exposure concentration was 0.030 mg/L (NOEC), which was above water solubility.
The 96h-LC50 was above water solubility. Hence, due to the extremely low water solubility of the test substance, concentration levels toxic for fish could not be reached.
Setafix X 11342 inhibited cell growth and reduced growth rate of this fresh water algae species significantly in filtrates prepared at loading rates of 50 and 100 mg/l. This could at least partly be attributed to impurities. Cell growth and growth rate were not affected in solutions where the initial concentration approximated the water solubility of the main component. The EC50 for cell growth and growth rate were above water solubility. The NOEC for both cell growth inhibition and growth rate reduction was 0.042 mg/l when based on initial concentrations, and 0.011 mg/l when based on average exposure concentrations.
No inhibition of respiration rate of the sludge was recorded at 100 mg Setafix X 11342 per litre. The duplicate measurement confirmed the result of the first measurement. Therefore, no further testing was needed. In conclusion, under the conditions of this present test, Setafix X 11342 was not toxic to waste water (activated sludge) bacteria at a concentration of 100 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
