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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
23 Oct 2017 - 20 Nov 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
2009
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
2006
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7950 (Vapor Pressure)
Version / remarks:
1996
Deviations:
no
GLP compliance:
yes
Type of method:
effusion method: isothermal thermogravimetry

Test material

Constituent 1
Chemical structure
Reference substance name:
(6S)-6-(propylamino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrobromide
EC Number:
605-420-3
Cas Number:
165950-84-5
Molecular formula:
C13H20BrNO
IUPAC Name:
(6S)-6-(propylamino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrobromide
Test material form:
solid: particulate/powder
Details on test material:
- Appearance: White powder
- Storage condition of test material: At room temperature

Results and discussion

Vapour pressureopen allclose all
Key result
Temp.:
20 °C
Vapour pressure:
< 0 Pa
Key result
Temp.:
25 °C
Vapour pressure:
< 0 Pa

Any other information on results incl. tables

Table: Results of the isothermal TGA analysis (test item)

Temperature
[°C]

Weight loss
[µg/min]

νT
[g/cm2/h]

log νT

log PT

PT
[Pa]

200

2.06578

2.47 x 10-4

-3.61

0.52

3.3

 

2.10068

2.51 x 10-4

-3.60

0.53

3.4

210

4.12797

4.93 x 10-4

-3.31

0.90

8.0

 

4.21660

5.03 x 10-4

-3.30

0.92

8.2

220

7.97171

9.52 x 10-4

-3.02

1.27

19

 

7.93892

9.48 x 10-4

-3.02

1.27

18

230

14.1044

1.68 x 10-3

-2.77

1.59

39

 

14.3931

1.72 x 10-3

-2.76

1.60

40

Applicant's summary and conclusion

Conclusions:
The vapour pressure of the substance at 20°C was determined to be < 1.3E-8 Pa.
The vapour pressure of the substance at 25°C was determined to be < 7.2E-8 Pa.
Executive summary:

The vapour pressure of the substance was determined using the isothermal thermogravimetric effusion method in a GLP study according to EC A.4, OECD 104 and OPPTS 830.7950.

The constants specific for the experimental arrangement were determined using a set of 5 reference compounds. A vapour pressure curve for the test item was constructed from duplicate measurements at 200°C, 210°C, 220°C and 230°C. The vapour pressure of the substance at 20°C and 25°C were calculated from the vapour pressure regression curve to be outside the validated range of the method. According to this, the vapour pressure of the test item was determined to be lower than that of benzo(ghi)perylene, the reference compound with the lowest vapour pressure. The vapour pressure of the substance at 20°C and 25°C were therefore determined to be < 1.3E-8 Pa and < 7.2E-8 Pa, respectively.