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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1976
Report date:
1976

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 401 (Acute Oral Toxicity)
GLP compliance:
no
Test type:
standard acute method
Limit test:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
2-hexylcyclopent-2-enone
EC Number:
202-417-5
EC Name:
2-hexylcyclopent-2-enone
Cas Number:
95-41-0
Molecular formula:
C11H18O
IUPAC Name:
2-hexylcyclopent-2-en-1-one
Test material form:
liquid

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified
Doses:
5000 mg/kg bw
No. of animals per sex per dose:
10 animals used
Control animals:
no
Details on study design:
- Duration of observation period following administration: 14 days
- Examinations performed: mortality and toxicity

Results and discussion

Effect levels
Key result
Sex:
not specified
Dose descriptor:
discriminating dose
Effect level:
5 000 mg/kg bw
Based on:
test mat.
Mortality:
No mortality observed
Clinical signs:
other: Diarrhea was observed on day 1 and 2. Lethargy was observed on day 4.

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met