Registration Dossier

Ecotoxicological information

Short-term toxicity to fish

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to fish
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Reference:
Composition 0
Qualifier:
no guideline followed
Principles of method if other than guideline:
Estimation of Toxicity to Aquatic Organisms Using ECOSAR v2.0
- Water solubility selected: 252.21 mg/L (measured)
- Partition coefficient selected: 2.3 (measured)
Test material information:
Composition 1
Key result
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
99.85 mg/L
Nominal / measured:
estimated
Conc. based on:
test mat.

Description of key information

The estimated 96h-LC50 is 99.85.

Key value for chemical safety assessment

LC50 for freshwater fish:
99.85 mg/L

Additional information

For the assessment of the aquatic toxicity of the test substance to fish, QSAR results were used. ECOSAR v2.0 was used as the QSAR model and a water solubility of 252.21 mg/L and a partition coefficient of 2.3 was used for the prediction of the aquatic toxicity in fish. The results fell within the applicability domain of the QSAR model and subsequently the criteria listed in Annex XI of Regulation (EC) No 1907/2006 chapter 1.3 are considered to be fulfilled. Therefore, other studies on aquatic toxicity in fish are not provided.