Registration Dossier
Registration Dossier
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EC number: 948-046-9 | CAS number: -
Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 26 September 2017 to ****
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- HPLC estimation method
- Media:
- sewage sludge
- Specific details on test material used for the study:
- Physical state: Dark amber liquid
Purity: >93 % - Test temperature:
- 25 °C
- Details on study design: HPLC method:
- UV detection: 210 nm
- Key result
- Type:
- log Koc
- Value:
- < 5.61 dimensionless
- pH:
- 5
- Temp.:
- 25 °C
- Remarks on result:
- other: same result at pH 7 and 9
- Validity criteria fulfilled:
- yes
- Conclusions:
- The adsorption coefficient of the test material has been determined to have a log Koc of greater than 5.63.
- Executive summary:
In a study performed to the standardised guideline OECD 121, under GLP conditions; the adsorption coefficient of the test material has been determined to have a log Koc of greater than 5.63, Smithers Viscient (ESG) Ltd (2018).
Reference
The retention time for the test substance was greater than that of DDT for pH 5, 7 and 9 and when the result was extrapolated based the calibration line, the mean log Koc was 6.5 for pH 5, 7 and 9. This demonstrates that the pH had no effect on the adsorption coefficient. The standard with the highest log Koc is DDT at 5.63 so no degree of certainty can be attached to the extrapolated value of 6.5 value. The log Koc is therefore considered to be >5.63.
Description of key information
In a study performed to the standardised guideline OECD 121, under GLP conditions; the adsorption coefficient of the test material has been determined to have a log Koc of greater than 5.63, Smithers Viscient (ESG) Ltd (2018).
Key value for chemical safety assessment
Additional information
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