Registration Dossier
Registration Dossier
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EC number: 205-027-3 | CAS number: 131-54-4
Endpoint summary
Administrative data
Description of key information
Aquatic invertebrates (freshwater)
- Short-term toxicity to aquatic invertebrates: LC50 (48 h) = 14 mg/L for Daphnia magna based on mortality (static, no infomation about guideline and GLP compliance)
- Short-term toxicity to aquatic invertebrates: LC50 (48 h) = 2.983 mg/L for Daphnia magna based on mortality (QSAR/ECOSAR prediction)
- Short-term toxicity to aquatic invertebrates: EC50 (48 h) = 4.865 mg/L for Daphnia magna based on mobility (QSAR/SciQSAR prediction)
- Short-term toxicity to aquatic invertebrates: EC50 (48 h) = 42.828 mg/L for Daphnia magna based on mobility (QSAR/Leadscope prediction)
- Short-term toxicity to aquatic invertebrates: LC50 (24 h) = 7.63 mg/L for Dugesia japonica based on mortality (static, according to Chinese National Standards (GB/T 16125-2012), GLP not specified)
Aquatic algae and cyanobacteria (freshwater)
- Toxicity to aquatic algae and cyanobacteria: EC50 (96 h) = 1.31 mg/L based on growth rate for algae (QSAR/ECOSAR prediction)
- Toxicity to aquatic algae and cyanobacteria: EC50 (72 h) = 16.799 mg/L based on growth rate for algae (QSAR/SciQSAR prediction)
- Toxicity to aquatic algae and cyanobacteria: EC50 (72 h) = 18.785 mg/L based on growth rate for algae (QSAR/Leadscope prediction)
- Toxicity to aquatic algae and cyanobacteria: EC50 (96 h) = 6.86 mg/L based on growth rate for Chlorella vulgaris (according to Chinese National Standards (GB/T 21805-2008), GLP not specified)
Additional information
Based on the acute toxicity data for aquatic invertebrates and algae the registered substance 2,2'-Dihydroxy-4,4'-dimethoxybenzophenone (Benzophenone-6, BP-6) does not need to be classified as acute toxic to the aquatic environment. With regard to chronic toxicity, taking into account the facts that the test item is soluble in water, i.e. water solubility is above the determined EC50 value, and not readily biodegradable, the test item should be classified as aquatic chronic Cat. 2 according to Regulation (EC) No 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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