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EC number: 947-957-9
CAS number: -
Skin: Category 1B (corrosive) based on GHS criteria
Studies waived for eye irritation and respiratory based on the findings
of skin corrositivity.
In a study performed in accordance with US D.O.T. regulations and OECD
404, the test item was applied to three prepared skin sites on New
Zealand White rabbits under occluded conditions for 3 minutes, 1
hour and 4 hours. After the relevant contact period, any remaining test
item was wiped from the site. After removal of patches and 24, 48 and 72
hours later, the test sites were examined for evidence of
primary irritation and scored for erythema. No effects were noted over a
period of 60 minutes following contact with the test item for 3 minutes.
However, occluded contact with the test item for one hour
produced severe irritation (erythema scores at 24/48/72 hours ≥ 2.3 in
5/6 animals) and necrosis was observed in three of the six animals
within 7 days. On the basis of this study, the test material is found
to be corrosive to skin.
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