Registration Dossier

Administrative data

Endpoint:
eye irritation: in vitro / ex vivo
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2018
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report Date:
2018

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 437 (Bovine Corneal Opacity and Permeability Test Method for Identifying i) Chemicals Inducing Serious Eye Damage and ii) Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage)
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder

Test animals / tissue source

Species:
cattle

Test system

Vehicle:
water
Controls:
yes, concurrent vehicle
yes, concurrent positive control

Results and discussion

In vitro

Results
Irritation parameter:
in vitro irritation score
Value:
ca. 1
Vehicle controls valid:
yes
Positive controls valid:
yes

Applicant's summary and conclusion

Conclusions:
Under the experimental conditions of this study, the test item, HTP 6123 DIDOPO, was identified as not requiring classification for eye irritation or serious eye damage (UN GHS No Category).