2,2'-[oxybis(2,1-ethanediyloxy)]bisacetic acid

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

from 2018-03-29 to 2018-04-23

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7220 (Boiling Point / Boiling Range)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

method according to Siwoloboff

Specific details on test material used for the study:

Batch no.: 03/2016_T_R_JM

Key result

Boiling pt.:

281.3 °C

Atm. press.:

99.37 kPa

Decomposition:

yes

Decomp. temp.:

> 281.3 °C

Reference Test

The apparatus was checked with ultrapure water.

Table 1. The checking of apparatus

03 April 2018
Atmospheric pressure, kPa (at the measuring)	Boiling point, °C (at standard atmospheric pressure)
99.37	100.0
99.36	99.9
99.37	100.0
Mean:	100.0

The boiling point of water was determined to be 100.0 °C (373.1 K). Measured values were determined to be in the required range (literature value ± 0.5 °C).

 

Preliminary Test

Preliminary test was performed before the main test. At the end of the measurement bumping was recorded by the device.

Table 2. Preliminary Test

Start temperature, °C	Heating rate, °C/min	Atmospheric pressure, kPa (at the measuring)	Boiling point, °C (at standard atmospheric pressure)
25	5	99.37	276.6

 

Boiling point of Test Item

For the main study the metal block was heated to 265 °C. The capillaries containing the test item were placed into the apparatus and the temperature was raised at 1 °C/min heating rate until the boiling temperature was reached. Three tests were carried out. The boiling temperature was determined and the boiling point of the test item was determined to be 281.3 ± 8.13 °C (95 % confidence interval) i.e. 554.5 K. At the end of the measurements bumping was observed.

Before the test the appearance of the test item was colourless, viscous liquid. At the end of the measurements the color of the samples became light brown in the capillary.

Table 3. Determination of the Boiling Point of the test item

Atmospheric pressure, kPa (at the measuring)	Boiling point, °C (at standard atmospheric pressure)
99.37	278.5
99.39	280.5
99.37	284.9
Mean:	281.3
RSD (CV %):	1.2
Conf.int. (95 %)	8.13

 

Based on this signal, a relatively large deviation between the individual measurements and the appearance of test item after the tests, the 554.5 K is considered to be a decomposition temperature.

Conclusions:

The boiling temperature was determined to be 554.5 K (281.3 °C). At the end of the tests bumping was recorded. Based on this result and change in appearance of the test item after the test, it can be concluded that the test item decomposes at 281.3 °C.

Executive summary:

A study was conducted according to OECD test guideline 103, Regulation (EC) No 440/2008 method A.2 and EPA OPPTS 830.8220 to determine the boiling point of the test item using the principle according to Siwoloboff. A small amount of the test item was filled in a capillary tube using centrifuge and was heated in the electronically temperature controlled sample block. In a preliminary test a boiling point of 276 °C was observed. This value was introduced as expected boiling temperature for the main test. The sample was heated from 265 °C at rate 1 °C/minute. The sample was observed visually for any possible changes in appearance, consistency and colour. The phase transition from liquid to vapour was deduced by the continuous formation of steam bubbles leaving the inserted boiling capillary. This determination was done in triplicate. The atmospheric pressure was recorded. The boiling point was determined to be 281.3 °C i.e. 554.5 K at 99.37 kPa. At the end of the measurements bumping was recorded and the test items appearance was changed from colourless viscous liquid to light brown liquid in the capillary. Based on these results, it can be considered that the test item decomposes at 281.3 °C.

Description of key information

The boiling temperature was determined to be 554.5 K (281.3 °C). At the end of the tests bumping was recorded. Based on this result and change in appearance of the test item after the test, it can be concluded that the test item decomposes at 281.3 °C.

Key value for chemical safety assessment

Boiling point at 101 325 Pa:

281.3 °C

Additional information

A study was conducted according to OECD test guideline 103, Regulation (EC) No 440/2008 method A.2 and EPA OPPTS 830.8220 to determine the boiling point of the test item using the principle according to Siwoloboff. A small amount of the test item was filled in a capillary tube using centrifuge and was heated in the electronically temperature controlled sample block. In a preliminary test a boiling point of 276 °C was observed. This value was introduced as expected boiling temperature for the main test. The sample was heated from 265 °C at rate 1 °C/minute. The sample was observed visually for any possible changes in appearance, consistency and colour. The phase transition from liquid to vapour was deduced by the continuous formation of steam bubbles leaving the inserted boiling capillary. This determination was done in triplicate. The atmospheric pressure was recorded. The boiling point was determined to be 281.3 °C i.e. 554.5 K at 99.37 kPa. At the end of the measurements bumping was recorded and the test items appearance was changed from colourless viscous liquid to light brown liquid in the capillary. Based on these results, it can be considered that the test item decomposes at 281.3 °C.