Registration Dossier

Physical & Chemical properties

Partition coefficient

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
26-08-2017 - 26-08-2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
Experimental test result performed using standard test guidelines
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
GLP compliance:
no
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
1.394
Temp.:
25 °C
pH:
7.2
Remarks on result:
other: no other details available

Test substance

 

K

Log k

Log Pow by Generalized Calibration

Graph

Mean of Log Pow ± S.D.

tR1

1.502

0.671

-0.173

1.391

1.394 ± 0.005

tR2

1.505

0.674

-0.17

1.398

Conclusions:
The partition coefficient(n-octanol/water) of test substance Reaction mass of Cardanol diene and Cardanol monoene and Cardanol triene was determined as per the HPLC method(OECD Guideline-117). The Log Pow value was determined to be 1.394 ± 0.005 at 25°C.
Executive summary:

The partition Coefficient n-octanol/water of Reaction mass of Cardanol diene and Cardanol monoene and Cardanol triene was determined by the Reverse Phase High Performance

Liquid Chromatographic method according to OECD Guideline No. 117 for testing of Chemicals.The reference substances were chosen according to

functional similarity with the test substance and calibration graph was prepared . The reference substances were Triphenylamine Toluene, Ethylbenzene, n-

Butylbenzene, Naphthalene having Pow value ranging from 2.7 to 5.7 The Log Pow value was determined to be 1.394 ± 0.005 at 25°C.

On the basis of log Pow value it can be concluded that test chemical is hydrophilic in nature.

Description of key information

             

The partition Coefficient n-octanol/water of Reaction mass of Cardanol diene and Cardanol monoene and Cardanol triene was determined by the Reverse Phase High Performance

Liquid Chromatographic method according to OECD Guideline No. 117 for testing of Chemicals.The reference substances were chosen according to

functional similarity with the test substance and calibration graph was prepared . The reference substances were Triphenylamine Toluene, Ethylbenzene, n-

Butylbenzene, Naphthalene having Pow value ranging from 2.7 to 5.7 The Log Pow value was determined to be 1.394 ± 0.005 at 25°C.

On the basis of log Pow value it can be concluded that test chemical is hydrophilic in nature.

Key value for chemical safety assessment

Log Kow (Log Pow):
1.394

Additional information

The partition Coefficient n-octanol/water of Reaction mass of Cardanol diene and Cardanol monoene and Cardanol triene was determined by the Reverse Phase High Performance

Liquid Chromatographic method according to OECD Guideline No. 117 for testing of Chemicals.The reference substances were chosen according to

functional similarity with the test substance and calibration graph was prepared . The reference substances were Triphenylamine Toluene, Ethylbenzene, n-

Butylbenzene, Naphthalene having Pow value ranging from 2.7 to 5.7 The Log Pow value was determined to be 1.394 ± 0.005 at 25°C.

On the basis of log Pow value it can be concluded that test chemical is hydrophilic in nature.