Amides, C18-unsatd., N-hydroxyethyl

Auto flammability

Administrative data

Endpoint:

relative self-ignition temperature (solids)

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance is a solid having a melting point <= 160°C

Cross-reference

Reason / purpose for cross-reference:

data waiving: supporting information

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From April 02, 2018 to April 23, 2018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

other: OCSPP 830.7220

Version / remarks:

Melting Range recorded during boiling point determination

Deviations:

no

Remarks:

A third replicate for melting point analysis was performed due to the calculated %diff was 7.8% at the initial melting stage. There is considered to be no impact on the results of the study

GLP compliance:

yes

Type of method:

other: The test article is placed in a boiling point apparatus for analysis. The test article will initially go through a melting stage prior to reaching the boiling point. The temperature range, at which the test article melts, is recorded as the melting point.

Key result

Melting / freezing pt.:

>= 25.4 - <= 46 °C

Atm. press.:

101.7 kPa

Decomposition:

no

2-Propanol was used as the reference material with known boiling point to verify the procedure. A boiling point of 83.9 °C was obtained which is acceptable when compared to a published value of 82.3 °C. Local atmospheric pressure of 101.7 kPa was taken from the Environment Canada website at www.weatheroffice.gc.ca (Vancouver International Airport, located in Richmond BC, approximately 30 km southwest of the Test Facility). Before boiling, the test article underwent a melting stage, which was recorded as Initial Melt Stage A (beginning – when fine droplets adhere uniformly on the inside of apparatus) and Final Melt Stage E (end – no solid particles remaining)

Determination of Melting Point

GX5301	Melting Start Stage A Temp (°C)	Melting Complete Stage E Temp (°C)
Replicate 1 (2Apr2018)	23.5	45.9
Replicate 2 (2Apr2018)	25.4	46.8
Replicate 3 (23Apr2018)	27.2	45.2
Mean	25.4	46.0
SD	1.85	0.80
%RSD	7.3	1.7

 

Conclusions:

Under the study conditions, the melting point of the test substance was determined to be in range of ≥25.4 to ≤46.0°C.

Executive summary:

A study was conducted to determine the melting point of the test substance according to OCSPP 830.7220, in compliance with GLP. Before boiling, the test substance underwent a melting stage, which was recorded as initial melt stage A (beginning – when fine droplets adhere uniformly on the inside of apparatus) and final melt stage E (end – no solid particles remaining). Under the study conditions, the melting point of the test substance was determined to be in range of ≥25.4 to ≤46.0°C (Meghan, 2018).