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EC number: 201-335-7 | CAS number: 81-23-2
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Qualifier:
- according to
- Guideline:
- EU Method A.6 (Water Solubility)
- Qualifier:
- according to
- Guideline:
- other: CIPAC MT 157
- GLP compliance:
- yes
- Type of method:
- column elution method
Test material
Reference
- Name:
- Unnamed
- Type:
- Constituent
- Test material form:
- solid: crystalline
- Specific details on test material used for the study:
- Batch number: 2016110462
Results and discussion
Water solubility
- Water solubility:
- 0.07 g/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- 5.4
Any other information on results incl. tables
Results
Data in the tables are rounded values taken from Excel spreadsheets which will be archived together with the raw data. The use of Excel spreadsheets for calculations produces more accurate endpoints. These endpoints may slightly differ from the values derived by replacing the rounded values in the formulae are given in the methods section.
For all the sample solutions the pH value was 5.4, measured by pH meter.
The quality criteria of the A.6 method were verified (RSD% over three values is < 15%).
Table7 Water Solubility: analytical results
Internal code | As | Cs (1) (mg/mL) | Ds | WaterSolubility (g/L) |
WS A | 110158 | 68.96 | 1 | 0.070 |
WS B | 112784 | 70.63 | 1 | 0.071 |
WS C | 114915 | 71.97 | 1 | 0.072 |
Mean value : | 0.07 | |||
Standard deviation (S.D.) : | 0.002 | |||
Relative Standard Deviation (RSD%) : | 2.14% | |||
(1) Quantification with the linear calibration curve.
Applicant's summary and conclusion
- Conclusions:
- Water solubility of the substance is 0.07 g/L
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