Registration Dossier
Registration Dossier
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EC number: 251-889-9 | CAS number: 34231-26-0
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Remarks:
- intraperitoneal
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods with acceptable restrictions
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 980
- Report date:
- 1980
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- BASF-Test
- GLP compliance:
- no
- Limit test:
- no
Test material
- Reference substance name:
- 1-amino-4-hydroxy-2-[(6-hydroxyhexyl)oxy]anthraquinone
- EC Number:
- 251-889-9
- EC Name:
- 1-amino-4-hydroxy-2-[(6-hydroxyhexyl)oxy]anthraquinone
- Cas Number:
- 34231-26-0
- Molecular formula:
- C20H21NO5
- IUPAC Name:
- 1-amino-4-hydroxy-2-[(6-hydroxyhexyl)oxy]-9,10-dihydroanthracene-9,10-dione
- Test material form:
- solid
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- not specified
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- no data
Administration / exposure
- Route of administration:
- intraperitoneal
- Vehicle:
- water
- Details on exposure:
- VEHICLE
- Concentration in vehicle: 0.5 to 30% - Doses:
- no data
- No. of animals per sex per dose:
- no data
- Control animals:
- no
- Details on study design:
- - Duration of observation period following administration: 7 days
- Frequency of observations and weighing: clinical signs daily, weighing weekly
- Necropsy of survivors performed: yes - Statistics:
- NA
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 50 - < 200 mg/kg bw
- Based on:
- test mat.
- Mortality:
- no data
- Clinical signs:
- no data
- Body weight:
- no data
- Gross pathology:
- no data
Applicant's summary and conclusion
- Conclusions:
- Based on the results from this study, the LD50 (intrapeitoneal) of the test item was determined to be > 50 and < 200 mg/kg bw. in mice.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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