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Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
August 2017
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
Justification for type of information:
Similar to a guideline method conducted within the spirit of GLP, but without GLP certification
Qualifier:
equivalent or similar to
Guideline:
ISO 13320 (Particle size analysis - Laser diffraction methods)
GLP compliance:
no
Type of method:
Laser scattering/diffraction
Type of particle tested:
primary particle
Type of distribution:
mass based distribution
Specific details on test material used for the study:
Vertellus 1,3-Di- 4-Piperidylpropane (DiPIP) flakes material, Lot #167742.
Key result
Percentile:
D10
Mean:
12.313 µm
Remarks on result:
other: fraction which passed through a 600 micron screen
Remarks:
Actual fraction: 0.04%
Key result
Percentile:
D50
Mean:
61.503 µm
Remarks on result:
other: fraction which passed through a 600 micron screen
Key result
Percentile:
D90
Mean:
141.346 µm
Remarks on result:
other: fraction which passed through a 600 micron screen
Remarks:
Actual fraction: 0.43%

Surface Weighted Mean: 18.170 um

Vol. Weighted Mean: 70.120 um

DT10: 12.313

DT50: 61.503

DT90: 141.346

 

The % volume of powder in the 0.56 g sieved material was found as follows:

<10µm size = 7.95%

<100µm size = 77.1%

 

When the above % volume is further calculated against the initial sample weight of 100.08 g DIPIP flaked material, the PSD result is calculated to be as follows:

<10µm size = 0.04%

<100µm size = 0.43%

Conclusions:
Gramulometry was assessed on the test material using a combination of seiving and LASER diffraction. Less than 1% of the material passed through a 600 micron sieve. Data from LASER diffraction showed that 0.04% of the test material is less than 10 microns (respirable), and 0.43% is less than 100 microns (inhalable). This documents that the commercial material has an extremely low risk of being inhaled by workers.

Description of key information

Percentage of flaked material < 600 microns: 0.56;

Percentage of flaked material < 100 microns: 0.43

Percentage of flaked material < 10 microns: 0.04

Additional information

Using seiving and LASER diffraction, less than 1% of the commercial material passed through a 600 micron sieve.  Approximately 0.04% is less than 10 microns (respirable), and 0.43% is less than 100 microns (inhalable), documenting that workers have an extremely low likelihood of inhaling particles of the commercial material into the respiratory trac