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EC number: 247-873-6
CAS number: 26650-05-5
72 h ErC10: 19 mg/L72 h ErC50: 98 mg/L
the Klimisch 1 GLP study from Vryenhoef (2016) the toxicity of
Butanedioic acid, sulfo-, 4-[2 -[(1 -oxo-10 -undecenyl)amino]ethyl]
ester, disodium salt to Pseudokirchneriella
subcapitata was determined in a static 72 Hour Algal Growth Inhibition
Test. The test item was an aqueos solution/suspension of the test
substance. The test concentrations were based on active ingredient. The
test was performed according to OECD 201 and EU Method C.3. The nominal
concentrations of 1.0, 3.2, 10, 32 and 100 mg ai/L were tested in
parallel with a control. Dose verification analysis was performed.
Analysis of the test preparations at 0 and 72 hours showed measured test
concentrations to be near nominal with the exception of the 3.2 mg ai/L
test sample at 72 hours where a measured concentration of 185% of
nominal was obtained. This was considered to be due to an error during
the analytical work up given that a measured concentration of 99% of
nominal was obtained at 0 hours. Given this it was considered
appropriate to calculate the results based on nominal test
cell density was determined at 0, 24, 48 and 72 hours. The cell
densities determined using a Coulter® Multisizer Particle Counter. Three
determinations were made for each sample. The nominally inoculated cell
concentration (5.00 x 10^3 cells/mL) was taken as the starting cell
growth of the control cultures fulfilled the validity criteria from OECD
201 (2006). The 72 -hour ErC10 and ErC50 are 19 and 98 mg a.i./L based
on nominal concentration.
results of this test are considered relevant and reliable for the risk
assessment of the registered substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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