Registration Dossier

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
0.144 mg/L
Assessment factor:
1 000
Extrapolation method:
assessment factor
PNEC freshwater (intermittent releases):
1.44 mg/L

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
0.014 mg/L
Assessment factor:
10 000
Extrapolation method:
assessment factor
PNEC marine water (intermittent releases):
0.144 mg/L

STP

Hazard assessment conclusion:
no emission to STP expected

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
3.238 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
0.324 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
1.523 mg/kg soil dw
Extrapolation method:
equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential to cause toxic effects if accumulated (in higher organisms) via the food chain

Additional information

Conclusion on classification

The toxicity to the aquatic environment of 1-[(2-hydroxyethyl)thio]propan-2-ol was investigated by performing GLP-compliant short-term toxicity studies to freshwater aquatic invertebrates and algae, and by performing an expert assessment on the short-term toxicity to freshwater fish based on valid QSAR predictions and literature data on an analogue substance.

Fish was identified as the most sensitive species based on the outcome of the investigation with a 96h LC50 of 144 mg/L. Considering that the lowest L(E)C50 for 1-[(2-hydroxyethyl)thio]propan-2-ol is above 1 mg/L, the substance does not meet the criteria for classification as Aquatic Acute 1; H400 in accordance with Regulation (EC) N° 1272/2008. 

There is no available data on the chronic toxicity of 1-[(2-hydroxyethyl)thio]propan-2-ol to the aquatic environment. As the substance is being registered under REACH in the 10-100 tonnage band there is no requirement for information on long-term studies to aquatic species. Therefore the classification of the registered substance for chronic effects is based on the short-term toxicity of 1-[(2-hydroxyethyl)thio]propan-2-ol to the aquatic environment and its ready biodegradability. Considering that the lowest L(E)C50 for 1-[(2-hydroxyethyl)thio]propan-2-ol is above 100 mg/L, the substance does not meet the criteria for classification for long lasting effects to the aquatic environment in accordance with Regulation (EC) N° 1272/2008.