Registration Dossier

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
oxidising liquids
Type of information:
other: An assessment was carried out based on an examination of the functionality within the substance
Adequacy of study:
key study
Study period:
2016
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: An assessment was carried out based on an examination of the functionality within the substance
Qualifier:
no guideline followed
Principles of method if other than guideline:
An assessment was carried out based on an examination of the functionality within the substance
GLP compliance:
no
Sample tested:
other: not applicable
Parameter:
other: An assessment was carried out based on an examination of the functionality within the substance, to identify the presence of elements commonly associated with oxidising behaviour.
Remarks on result:
other: see "other information on results"

According to the CLP Regulation (EC) No 1272/2008, Section 2.13.1, an oxidising liquid is defined as ‘a liquid substance or mixture which, while itself not necessarily combustible, may, generally by

yielding oxygen, cause, or contribute to, the combustion of other material.’ A screening procedure has been used to assess the oxidising properties of 1-[(2 -hydroxyethyl)thio]propan-2-ol. This has taken into consideration the following:

1. Annex VII of the REACH regulation ((EC) No 1907/2006), section 7.13, which states that a study of the oxidising behaviour of a substance need not be conducted if the substance ‘is incapable of reacting exothermically with combustible materials, for example on the basis of chemical structure (e.g. organic substances not containing oxygen or halogen atoms and these elements are not chemically bonded to nitrogen or oxygen.’)

2. Section 2.13.4.1 of the CLP regulation covering oxidising liquids states that for organic substances, the classification procedure shall not apply if:

a. The substance does not contain oxygen, fluorine or chlorine; or

b. The substance contains oxygen, fluorine or chlorine and these elements are chemically bonded to carbon or hydrogen.

An evaluation of the functionality within the substance has been performed to identify the presence of elements commonly associated with oxidising behaviour. Typical oxidising agents contain functional groups such as halide-oxygen groups, nitrogen-oxygen groups and some metal-oxygen complexes. The raw materials used to manufacture the substance do not contain any halogens, nitrogen, or metals, and these elements are not present in the final product. Although oxygen is contained within substance, it is chemically bonded to carbon and/or hydrogen and therefore does not significantly contribute to the oxidising potential of the substance. In addition, 1-[(2 -hydroxyethyl)thio]propan-2-ol does not meet the criteria for classification as an oxidising solid, see Section 2.13.4.1 of the CLP regulation.

Interpretation of results:
GHS criteria not met
Conclusions:
1-[(2-hydroxyethyl)thio]propan-2-ol does not have oxidising potential and does not require classification as an oxidising agent.
Executive summary:

An expert assessment was carried out based on an examination of the functionality within the substance, to identify the presence of elements commonly associated with oxidising behaviour. This compound contains two oxygen atoms and one chlorine atom. However, these are covalently bound only to carbon atoms and not nitrogen or oxygen. Therefore it is concluded that 1-[(2-hydroxyethyl)thio]propan-2-ol does not have oxidising potential and does not require classification as an oxidising agent.

Description of key information

An expert assessment was carried out based on an examination of the functionality within the substance, to identify the presence of elements commonly associated with oxidising behaviour. This compound contains two oxygen atoms and one chlorine atom. However, these are covalently bound only to carbon atoms and not nitrogen or oxygen. Therefore it is concluded that 1-[(2-hydroxyethyl)thio]propan-2-ol does not have oxidising potential and does not require classification as an oxidising agent.

Key value for chemical safety assessment

Oxidising properties:
non oxidising

Additional information

Justification for classification or non-classification