Registration Dossier

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
explosiveness, other
Type of information:
other: An assessment was carried out based on an examination of the functionality within the substance
Adequacy of study:
key study
Study period:
2016
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: An assessment was carried out based on an examination of the functionality within the substance
Qualifier:
no guideline followed
Principles of method if other than guideline:
An assessment was carried out based on an examination of the functionality within the substance.
GLP compliance:
no
Key result
Test series:
other: not applicable
Method:
other: expert assessment
Parameter:
other: functionality typically associated with explosive properties
Result:
other: According to the structural assessment carried out on 1-[(2-hydroxyethyl)thio]propan-2-ol, this substance is not expected to possess explosive properties
Remarks on result:
other: see 'any other information on results incl. tables'

An analysis of the substance has been performed in accordance with section 2.1.4.3 of the CLP regulation (EC 1272/2008). The assessment has been made with reference to the structural motifs that are listed in Table A6.1 in Appendix 6 of the UN RTDG, Manual of Tests and Criteria as being indicative of explosive behaviour in organic materials, to identify the presence of any structural features commonly associated with explosive behaviour.

 Functional Group  Comments/Conclusions
 C-C unsaturation (acetylenes, acetylides, 1,2-dienes)  Not present
 C-Metal and N-Metal (Grignard reagents, organo-lithium compounds)  Not present
 Contiguous N atoms (azides, aliphatic azo compounds, diazonium salts, hydrazines  Not present
 Contiguous O atoms (peroxides, ozonides)  Not present
 N-O (hydroxylamines, nitrates, nitro compounds, nitroso compounds, N-oxides)  Not present
 N-Halogen (chloramines, fluoroamines)  Not present
 O-Halogen (chlorates, perchlorates)  Not present

The raw materials used to manufacture the substance do not contain any halogens, nitrogen, or metals, and these elements are not present in the final product. Oxygen is contained within 1-[(2 -hydroxyethyl)thio]propan-2-ol, however it is not contained within a chemical group considered to be associated with explosive properties, as stated in section 2.1.4.3 of the CLP regulation.

It was concluded that 1-[(2-hydroxyethyl)thio]propan-2-ol does not have explosive properties and does not require classification for explosive properties.

Interpretation of results:
GHS criteria not met
Conclusions:
According to the structural assessment carried out on 1-[(2-hydroxyethyl)thio]propan-2-ol, this substance is not expected to possess explosive properties
Executive summary:

A structural assessment of 1-[(2-hydroxyethyl)thio]propan-2-ol for functionality typically associated with explosive properties was carried out. According to this assessment, this substance is not expected to possess explosive properties.

Description of key information

A structural assessment of 1-[(2-hydroxyethyl)thio]propan-2-ol for functionality typically associated with explosive properties was carried out. According to this assessment, this substance is not expected to possess explosive properties.

Key value for chemical safety assessment

Explosiveness:
non explosive

Additional information

Justification for classification or non-classification