Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Hydrolysis: waiving according to Annex XI of Regulation (EC) No. 1907/2006 (technically not feasible)

Ready Biodegradation: not readily biodegradable in the 10d-window and after 28 days; percentage biodegradation was 39% after 28 days

Bioaccumulation: log BCF of 0.5, estimated with BCFBAF model (v. 3.01)

Adsorption /desorption: waiving according to Annex VIII, column 2 of Regulation (EC) No. 1907/2006

Additional information

Biodegradation

A reliable study is available on the ready biodegradability of the submission substance (RL2). The study was performed acc. to OECD 301B / CO2 Evolution (Modified Sturm Test) and in compliance with GLP. The pass level of a biodegradation > 60 % could not be reached in the 10d-window. The mean biodegradation of the test item came up to 39% after 28 days. Consequently, the test substance must be regarded not readily biodegradable in the 10d-window and after 28 days. The study was considered adequate and reliable for the evaluation of the ready biodegradability of the submission substance.

Bioaccumulation

Data on bioaccumulation is only required according to Annex IX of Regulation (EC) No 1907/2006. However, a valid QSAR model was applied to estimate BCF for the PBT/vPvB assessment.

The log BCF was estimated with the Meylan et al. method of the BCFBAF software (v. 3.01), a valid well-documented model. The log BCF was estimated by BCFBAF to be 0.5 (RL2). In conclusion, the submission substance is not expected to bioaccumulate in organisms.

Transportation and distribution

Waiving according to Annex VIII, column 2 of Regulation (EC) No. 1907/2006: The study does not need to be conducted if based on the physicochemical properties the substance can be expected to have a low potential for adsorption (e.g. the substance has a low octanol water partition coefficient).