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Physical & Chemical properties

Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
GLP compliance:
yes
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Analytical method:
liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
> 1.2 - < 1.9
Temp.:
24 °C
pH:
7.5
Details on results:
The partition coefficient n-octanol / water (POW) of the test item was determined according to OECD guideline no. 117 [adopted on 13 April 2004] and EU test method A.8 [Council Regulation (EC) No 440/2008 of 30 May 2008] with the HPLC method.

Partition coefficient n-octanol / water (POW): log POW = 1.2 – 1.9 (upper and lower limits) / 2.2
(23.7 to 24.1 °C)
Conclusions:
The partition coefficient n-octanol / water (POW) of the test item was determined according to OECD guideline no. 117 [adopted on 13 April 2004] and EU test method A.8 [Council Regulation (EC) No 440/2008 of 30 May 2008] with the HPLC method.

Partition coefficient n-octanol / water (POW): log POW = 1.2 – 1.9 (upper and lower limits) / 2.2 (23.7 to 24.1 °C)
Executive summary:

he partition coefficient n-octanol / water (POW) of the test item was determined according to OECD guideline no. 117 [adopted on 13 April 2004] and EU test method A.8 [Council Regulation (EC) No 440/2008 of 30 May 2008] with the HPLC method.

Partition coefficient n-octanol / water (POW): log POW = 1.2 – 1.9 (upper and lower limits) / 2.2 (23.7 to 24.1 °C)

Description of key information

The partition coefficient n-octanol / water (POW) of the test item was determined according to OECD guideline no. 117 [adopted on 13 April 2004] and EU test method A.8 [Council Regulation (EC) No 440/2008 of 30 May 2008] with the HPLC method.

Partition coefficient n-octanol / water (POW): log POW = 1.2 – 1.9 (upper and lower limits) / 2.2 (23.7 to 24.1 °C)

Key value for chemical safety assessment

Log Kow (Log Pow):
1.9
at the temperature of:
24 °C

Additional information