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Physical & Chemical properties

Partition coefficient

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
25 November 2012 to 11 January 2013
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Version / remarks:
2004
GLP compliance:
no
Other quality assurance:
ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
4.7
Temp.:
35 °C
Remarks on result:
other: pH value was not reported

The retention times, capacity factors and Log Pow values determined for the sample are shown in the following table.

 

Sample name

Injection

Retention time [min]

Capacity factor (k)

Log k

Log Pow

Test substance

1

4.675

1.55

0.19

4.7

2

4.644

1.53

0.19

4.7

Average

4.660

1.54

0.19

4.7

 

 

Conclusion

The partition coefficient of the test material was determined to be Log Pow = 4.7 (calculated value by HPLC calibration plot).

Conclusions:
A log Pow of 4.7 at 35 °C was determined for the test substance according to OECD guideline 117.

Description of key information

Log Kow: 4.7 at 35 °C (OECD guideline 117, HPLC method)

Key value for chemical safety assessment

Log Kow (Log Pow):
4.7
at the temperature of:
35 °C

Additional information