Registration Dossier
Registration Dossier
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EC number: 235-920-3 | CAS number: 13047-13-7
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- abstract
Data source
Reference
- Reference Type:
- other: abstract
- Title:
- Unnamed
- Year:
- 1 992
- Report date:
- 1992
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: DIN 38412, Teil 15
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 4-(hydroxymethyl)-4-methyl-1-phenylpyrazolidin-3-one
- EC Number:
- 235-920-3
- EC Name:
- 4-(hydroxymethyl)-4-methyl-1-phenylpyrazolidin-3-one
- Cas Number:
- 13047-13-7
- Molecular formula:
- C11H14N2O2
- IUPAC Name:
- 4-(hydroxymethyl)-4-methyl-1-phenylpyrazolidin-3-one
- Test material form:
- solid: particulate/powder
Constituent 1
- Specific details on test material used for the study:
- batch: 579/80
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- yes
- Remarks:
- tap water
Test organisms
- Test organisms (species):
- Leuciscus idus melanotus
- Details on test organisms:
- TEST ORGANISM
- Common name: Goldenorfe
- Source: Fischzucht Eggers, 2354 Hohenwestedt
- Length at study initiation: 5-8 cm
ACCLIMATION: no data
FEEDING DURING TEST: no data
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Remarks on exposure duration:
- According to OECD 203 the test duration should be 96 hours
Test conditions
- Hardness:
- no data
- Test temperature:
- 20 ± 1°C
- pH:
- 7.97-8.23
- Dissolved oxygen:
- no data
- Nominal and measured concentrations:
- nominal:
pre-test: 10, 100 and 1000 mg/L
main test: 10, 20, 25, 35 and 50 mg/L - Details on test conditions:
- 1 fish/liter; 10 fish/concentration; test under continuous aeration
- Reference substance (positive control):
- no
Results and discussion
Effect concentrations
- Key result
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 35 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- pre-test showed 0% mortality at 10 mg/L and 100% mortality at 100 and 1000 mg/L
Any other information on results incl. tables
- Sublethal observations / clinical signs:
Concentration (mg/L)
Mortality at 48 hours
10
0/10
20
0/10
25
0/10
35
7/10
50
10/10
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The LC50 is 35 mg/L under the conditions of the test
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