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Physical & Chemical properties

Particle size distribution (Granulometry)

Administrative data

Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report Date:
2017

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
ISO 13320 (Particle size analysis - Laser diffraction methods)
Deviations:
no
Qualifier:
according to
Guideline:
other: CIPAC MT 187
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
Laser scattering/diffraction
Type of particle tested:
agglomerate
Type of distribution:
volumetric distribution

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: crystalline
Remarks:
light yellow
Details on test material:
CH03216 / E1A

Results and discussion

Mass median aerodynamic diameter:
26.805 µm
Geometric standard deviation:
0.004
Particle sizeopen allclose all
Percentile:
D10
Mean:
8.645 µm
St. dev.:
0.022
Percentile:
D50
Mean:
22.818 µm
St. dev.:
0.111
Percentile:
D90
Mean:
59.434 µm
St. dev.:
0.556

Applicant's summary and conclusion

Conclusions:
The results of the laser diffraction test conducted to determine the particle size of 3,4,5- Trimethoxycinnamic Acid are summarised below. The analysis was conducted using the dry powder module (DPM).

Volume weighted mean: 29.754 µm
Median 22.818 µm
Mode 22.996 µm
MMAD (mass median aerodynamic diameter) 26.805 µm
d10 - 10 % of material is < 8.645 µm
d50 - 50 % of material is < 22.818 µm
d90 - 90 % of material is < 59.434 µm
volume of sample < 10.00 μm 13.47 %