Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Toxicity studies in fish, aquatic invertebrates and algae have been conducted for 4,4’-(1-phenylethane-1,1-diyl)bis(heptyloxybenzene), and are included in the dossier. These Key studies are summarised below. All of the acute toxicity values are unbounded and greater than the limit of solubility of the test substance. No adverse effects were observed in any of the acute toxicity tests.

A reliable short-term toxicity study with fish (Cyprinus carpio)is available with a 96-hour LC50 (mortality) of >1.3 mg/L for 4,4’-(1-phenylethane-1,1-diyl)bis(heptyloxybenzene). Consequently, this value will be taken as the short-term toxicity in fish endpoint for 4,4’-(1-phenylethane-1,1-diyl)bis(heptyloxybenzene).

A reliable short-term toxicity study with aquatic invertebrates is available, with a 48-hour EC50 (immobility) of >15 ug/L 4,4’-(1-phenylethane-1,1-diyl)bis(heptyloxybenzene). Consequently, this value will be taken as the short-term toxicity in aquatic invertebrates endpoint for 4,4’-(1-phenylethane-1,1-diyl)bis(heptyloxybenzene).

A reliable toxicity study with freshwater algae is available, with a 72-hour EC50 (growth rate) of >1.4 ug/L for 4,4’-(1-phenylethane-1,1-diyl)bis(heptyloxybenzene). Consequently, this value will be taken as the toxicity in algae endpoint for 4,4’-(1-phenylethane-1,1-diyl)bis(heptyloxybenzene).

A reliable toxicity study with microorgansisms is available, with a 3-hour EC50 of >1000 mg/L for 4,4’-(1-phenylethane-1,1-diyl)bis(heptyloxybenzene). Consequently, this value will be taken as the toxicity in microorganisms endpoint for 4,4’-(1-phenylethane-1,1-diyl)bis(heptyloxybenzene).

Additional information