Registration Dossier
Registration Dossier
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EC number: 605-146-4 | CAS number: 158451-78-6
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The 72-h ErC50 and ErC10 values are both > 222 mg/L(based on active ingredient) in freshwater algae (P. subcapitata).
Key value for chemical safety assessment
Additional information
The toxicity towards freshwater algae was determined in a study according to OECD TG 201 and in compliance with GLP criteria. In this study, exponentially growing freshwater alga Pseudokirchneriella subcapitata were exposed to nominal test substance concentrations of 0 (control), 13.9, 27.8, 55.6, 111 and 222 mg/L based on active ingredient (corresponding to nominal test substance concentrations of 100, 200, 400, 800 and 1600 mg/L) for 72 hours under static conditions. Analytical confirmation of nominal test concentrations showed that all test concentrations remained well within ±20% of nominal concentrations throughout the test. Therefore, effect concentrations are expressed as nominal. At the start of the test and after 24, 48 and 72 hours exposure duration, the cell density was determined and inhibition of algal growth rate calculated. Throughout the test 2 - 9% inhibition of growth was observed, however without clear concentration-response relation. Based on these findings, both the 72-h ErC50 and ErC10 values were determined at > 222 mg a.i. /L.
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