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EC number: 946-533-0
CAS number: -
a subacute toxicity study Amphopropionate C8 (50.6% a.i.) was
administered to 3 female Wistar rats per dose orally by gavage once
daily at dose levels of 500 and 1000 mg/kg bw/day for 5 consecutive
days. The purpose of this study was to assess the tolerance of
rats to exposure of the test item for 5 days. The results of this study
were used to select the dose levels for the 28-day toxicity study.
animals survived the scheduled study period.
with the test item at the dose level of 1000 mg/kg bw/day caused a
slightly increased kidney weight and one animal of the high dose group
showed salivation between Day 3 and 5. No
further test substance-related findings were detected or observed in
clinical examinations, body weights, food consumption values and
clinical pathology evaluations including organ weight analysis.
on these results, dose levels of 0, 50, 150 and 1000 mg/kg bw/d were
considered suitable for the subsequent 28 day toxicity test.
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