Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Carcinogenicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no study available

Carcinogenicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
no study available

Carcinogenicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

Justification for classification or non-classification

Experimental data on carcinogenicity of Flurbiprofen t-butyl ester are not available.

 

As a results of the profiling of the substance performed by means QSAR Toolbox the structural alert "Halogenated aromatic hydrocarbon type compounds" has been identified. However, since a nucleophilic aromatic substitution mechanism (SNAr) has been proposed for halogenated aromatic compounds but one halogen is too weak to take part of SNAr reactions, this property is judged as inconclusive for the classification of the substance.