Registration Dossier

Physical & Chemical properties

Partition coefficient

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
19 May 2017 - 16 July 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
EU Method A.8 (Partition Coefficient - HPLC Method)
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Qualifier:
according to
Guideline:
EPA OPPTS 830.7570 (Partition Coefficient, n-octanol / H2O, Estimation by Liquid Chromatography)
GLP compliance:
yes (incl. certificate)
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Key result
Type:
log Pow
Partition coefficient:
4.58 - 5.44
Remarks on result:
other: For the amine components
Key result
Type:
log Pow
Partition coefficient:
5.88 - 6.5
Remarks on result:
other: For the sulfonate components
Conclusions:
The patition coefficient of the test material was determined to be log10 Pow 4.58 to 5.44 for the amine components and Log10 Pow 5.88 >6.5 for the sulfonate components.
Executive summary:

The partition coefficient of the test material was determined to be 3.77 x 10^4 to 2.77 x 10^5 (log10 Pow 4.58 to 5.44) for the amine components and 7.60 x 10^5 to greater than 3.16 x 10^6 (Log10 Pow 5.88 >6.5) for the sulfonate components using the HPLC method, designed to be compatible with A.8 Partition Coefficient of Commission Regulation No 440/2008, Method 117 of the OECD Guidelines for Testing of Chemicals and Method 830.7570 of the OCSPP Guidelines.

Description of key information

The partition coefficient of the test material was determined to be 3.77 x 10^4 to 2.77 x 10^5 (log10 Pow 4.58 to 5.44) for the amine components and 7.60 x 10^5 to greater than 3.16 x 10^6 (Log10 Pow 5.88 >6.5) for the sulfonate components using the HPLC method, designed to be compatible with A.8 Partition Coefficient of Commission Regulation No 440/2008, Method 117 of the OECD Guidelines for Testing of Chemicals and Method 830.7570 of the OCSPP Guidelines.

Key value for chemical safety assessment

Log Kow (Log Pow):
6.5

Additional information