Registration Dossier
Registration Dossier
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EC number: 252-652-2 | CAS number: 35642-64-9
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Data from autheritative database.
Data source
Reference
- Reference Type:
- other: autheritative database
- Title:
- Acute oral toxicity study for CAS no: 17804-49-8
- Author:
- U.S .National library of medicine
- Year:
- 2 017
- Bibliographic source:
- ChemIDplus A TOXNET DATABASE.2017
Materials and methods
- Principles of method if other than guideline:
- Acute oral toxicity study of Disodium 5-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]-4-hydroxy-3-(phenylazo)naphthalene-2,7-disulphonate (CAS no.: 17804-49-8) in rats.
- GLP compliance:
- not specified
- Test type:
- other: not specified
- Limit test:
- no
Test material
- Reference substance name:
- Disodium 5-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]-4-hydroxy-3-(phenylazo)naphthalene-2,7-disulphonate
- EC Number:
- 241-776-2
- EC Name:
- Disodium 5-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]-4-hydroxy-3-(phenylazo)naphthalene-2,7-disulphonate
- Cas Number:
- 17804-49-8
- Molecular formula:
- C19H10Cl2N6Na2O7S2
- IUPAC Name:
- disodium 5-[(dichloro-1,3,5-triazin-2-yl)amino]-4-hydroxy-3-[(E)-2-phenyldiazen-1-yl]naphthalene-2,7-disulfonate
- Details on test material:
- - Name of test material (as cited in study report):disodium 5-[(dichloro-1,3,5-triazin-2-yl)amino]-4-hydroxy-3-[(E)-2-phenyldiazen-1-yl]naphthalene-2,7-disulfonate
- Molecular formula :C19H10Cl2N6Na2O7S2
- Molecular weight :615.35g/mole
- Substance type:Organic
- Physical state:No data available
- Purity:No data available
- Impurities (identity and concentrations):No data available
Constituent 1
- Specific details on test material used for the study:
- - Name of test material (as cited in study report):disodium 5-[(dichloro-1,3,5-triazin-2-yl)amino]-4-hydroxy-3-[(E)-2-phenyldiazen-1-yl]naphth alene-2,7-disulfonate
- Molecular formula :C19H10Cl2N6Na2O7S2
- Molecular weight :615.35g/mole
- Substance type:Organic
- Physical state:No data available
- Purity:No data available
- Impurities (identity and concentrations):No data available
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- No data available
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- not specified
- Details on oral exposure:
- No data available
- Doses:
- 7460 mg/kg
- No. of animals per sex per dose:
- No data available
- Control animals:
- not specified
- Details on study design:
- No data available
- Statistics:
- No data available
Results and discussion
- Preliminary study:
- No data available
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 7 460 mg/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: 50% mortality was observed
- Mortality:
- 50% mortality was observed
- Clinical signs:
- other: No data available
- Gross pathology:
- No data available
- Other findings:
- No data available
Applicant's summary and conclusion
- Interpretation of results:
- other: Not classified
- Conclusions:
- LD50 was considered to be 7460.0 mg/kg body weight, when rats were treated with Disodium 5-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]-4-hydroxy-3-(phenylazo)naphthalene-2,7-disulphonate (CAS no.: 17804-49-8) via oral route.
- Executive summary:
Acute oral toxicity study was conducted in rats using Disodium 5-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]-4-hydroxy-3-(phenylazo)naphthalene-2,7-disulphonate (CAS no.: 17804-49-8) in rats. 50% mortality was observed at dose 7460mg/kg bw. Hence LD50 was considered to be 7460mg/kg body weight, when rats were treated Disodium 5-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]-4-hydroxy-3-(phenylazo)naphthalene-2,7-disulphonate via oral route.
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