Oligomeric reaction products of 4,4'-propane-2,2-diyldiphenol and 2-methyloxirane and 2-(chloromethyl)oxirane

Flash point

Link to relevant study record(s)

Reference

Endpoint:

flash point of flammable liquids

Type of information:

read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

key study

Study period:

16 September 2003 - 07 October 2003

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: GLP compliant study conducted in accordance with international guidelines.

Justification for type of information:

1. HYPOTHESIS FOR THE ANALOGUE APPROACH
Common functional groups and similar composition.

EP-4000s and the registered substance are very similar. They are UVBC substances and both are oligomeric reaction products of 4,4'-propane-2,2-diyldiphenol and 2-methyloxirane and 2-(chloromethyl)oxirane where constituents are structurally related. EP-4000s contains less than 0.1% monochlorinated constituents while the registered substance contains approximately 10% monochlorinated constituents. As these are otherwise structurally similar to other constituents it can be reasonably expected that EP-4000s and the registered substance will have essentially the same properties.

2. SOURCE AND TARGET CHEMICAL(S) (INCLUDING INFORMATION ON PURITY AND IMPURITIES)


EP4000s:
Purity 79.7-90%, 3 main components F, E, C
Impurities:
5 known by-products 18%
6 unknown impurities 2.4%
Water 0.1%
Chlorinated impurities <0.1%

Aliphaticdiol diglycidyl ether:
Purity 92.57%, 3 main components F, E, C
Impurities:
5 known by-products (same identity as EP-400s) 14.37%
Water none
Two new impurities (I and J) 10.48% in total

Further details are provided in Section 13 Assessment Reports

3. ANALOGUE APPROACH JUSTIFICATION

Read across all data – the presence of one chlorine atom in components comprising 10% of a relatively high molecular weight mixture will not have a significant effect on physicochemical properties. Furthermore, alky halides are known to have fire retardant properties and therefore impurities I and J will not confer any flammable properties. It is noted that the log Pow is determined on the three main components of EP-4000s which means if the test was repeated on the Aliphaticdiol diglycidyl ether the result would be the same as both substances have the same three main components.

Overall conclusion – no new information would be gained by testing Aliphaticdiol diglycidyl ether for physicochemical properties.

4. DATA MATRIX

Not applicable – read across based on similar composition for all physicochemical endpoints.

Purity 92.57%, 3 main components F, E, C
Impurities:
5 known by-products (same identity as EP-400s) 14.37%
Water none
Two new impurities (I and J) 10.48% in total

Further details are provided in Section 13 Assessment Reports

Reason / purpose for cross-reference:

read-across source

Qualifier:

according to guideline

Guideline:

EU Method A.9 (Flash-Point)

Deviations:

no

Qualifier:

according to guideline

Guideline:

ISO 2719 (Determination of flash point - Pensky-Martens closed cup method)

Version / remarks:

2002

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

closed cup

Flash point:

167 °C

Atm. press.:

101.3 kPa

In the preliminary test, a flash point of about 170°C was found. Therefore (flash point above 65°C expected), the main study was performed using the Pensky-Martens flash point tester.

The flash point was measured at each temperature with an increment of 2 K.

The main test was performed in duplicate.

A clear flash point was observed at a test item temperature of 166°C during both tests at the actual atmospheric pressure of 98.2 kPa.

Conclusions:

After correction for the atmospheric pressure, the flash point was determined to be 167 °C at 101.3kPa.

Description of key information

The flash point of Aliphaticdiol diglycidyl ether is 167°C at 101.3kPa using the Pensky-Martens closed cup flash point apparatus.

Key value for chemical safety assessment

Flash point at 101 325 Pa:

167 °C

Additional information

A determination of the flash point was conducted (RCC Ltd) according to the Pensky-Martens closed cup method.

In the preliminary test, a flash point of about 170°C was found.The main test was performed in duplicate. A clear flash point was observed at a test item temperature of 166°C during both tests at the actual atmospheric pressure of 98.2 kPa. After correction for the atmospheric pressure, the flash point of ADEKA RESIN EP-4000S was determined to be 167 °C at 101.3kPa.

The value of 167°C for the flash point of EP-4000s will be taken as the value for Aliphaticdiol diglycidyl ether.

Justification for read across justification - EP-4000s and Aliphaticdiol diglycidyl ether are very similar substances. They are UVBC subtances and both are oligomeric reaction products of 4,4'-propane-2,2-diyldiphenol and 2-methyloxirane and 2-(chloromethyl)oxirane where constituents are structurally related. EP-4000s contains less than 0.1% monochlorinated consitiuents while Aliphaticdiol diglycidyl ether contains approximately 10% monochlorinated constituents, but as these are otherwise structurally similar to other constituents it can be reasonably expected that EP-4000s and Aliphaticdiol diglycidyl ether will have essentially the same physicochemcial properties.

Based on the flash point value of 167 °C at 101.3kPa, Aliphaticdiol diglycidyl ether does not meet the classification criteria for a flammable liquid.