Registration Dossier

Administrative data

Description of key information

LD50 range by oral route: 3600 - 8500 mg/kg.

Key value for chemical safety assessment

Additional information

Oral:

Two studies with validity 3 according to Klimisch were available. As the LD50 in rat was in the range from 3600 to 8500 mg/kg, no key study was chosen and a "Weight of Evidence" approach was applied.

Dermal:

Only one unpublished study from RIFM was available. As it was with validity 3, no purpose flag was chosen. The result gave a LD50 above 5000 mg/kg.

Justification for classification or non-classification