Registration Dossier
Registration Dossier
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EC number: 200-562-9 | CAS number: 63-68-3
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
- EC50 for microorganisms:
- 10 000 mg/L
Additional information
No experimental data is available for L-methionine. The effect of D,L-methionine on the growth of Pseudomonas putida was determined in a GLP study (89 -0130 -DGO) with an EC50 of 10000 mg/l. Dawson and Jenkins (1950) showed that methionine is rapidly oxidized by activated sludge and showed no toxic effects to the microorganisms of activated sludge.
Read-across of D,L-methionine to L-methionine was used due to the structural similarities and the physicochemical similarities of the enantiomers. Further, both enantiomers are used by microorganisms as carbon source.
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