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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
13/04/2012-07/06/2012
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Reason / purpose:
reference to same study
Reference:
Composition 0
Qualifier:
according to
Guideline:
EPA OPPTS 830.7840 (Water Solubility)
Qualifier:
according to
Guideline:
EPA OPPTS 830.7860 (Water Solubility Generator Column Method)
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
yes
Type of method:
column elution method
Test material information:
Composition 1
Key result
Water solubility:
26.4 µg/L
Conc. based on:
test mat.
Temp.:
20 °C
pH:
> 6.47 - < 7.64
Remarks on result:
other:
Remarks:
pH of reagent water: 6.47 and an aqueous sample: 7.64
Details on results:
Under the instrumental conditions presented, the mean measured reagent water solubility of F-2200 HM, based on the primary component, at 20°C was 25.8 ± 2.0 μg/L (CV = 7.7%, N = 5) at a flow rate of approximately 1.0 mL/min and was 27.0 ± 0.43 μg/L (CV = 1.6%, N = 5) at a flow rate of approximately 0.5 mL/min. The mean measured F-2200 HM concentration as a function of flow-rate differed by 4.4%, which was well within the ±30% test criterion. The overall mean measured water solubility of F-2200 HM, based on the primary component, at 20°C was 26.4 ± 1.5 μg/L (CV = 5.7%, N = 10).
The mean measured reagent water solubility of F-2200 HM, based on the secondary component, at 20°C was less than the LOQ (20.0 μg/L) at both flow rates. The overall mean measured water solubility of F-2200 HM, based on the secondary component, at 20°C was less than the LOQ (20.0 μg/L).
The pH was measured for an aqueous sample collected at a flow rate of 1.0 mL/min. The measured pH of reagent water and an aqueous sample was 6.47 and 7.64, respectively.
Conclusions:
The water solubility of F-2200 HM, based on the primary component, in reagent water at 20oC using the column elution method was determined to be 26.4 ± 1.5 μg/L.
Executive summary:

The water solubility of F-2200 HM was meaured at 20oC by using the column elution method and was determined to be 26.4 ± 1.5 μg/L.

Description of key information

The water solubility of F-2200, based on the primary component, in reagent water at 20°C using the column elution method was 26.4 μg/L.

Key value for chemical safety assessment

Water solubility:
26.4 µg/L
at the temperature of:
20 °C

Additional information