Registration Dossier
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EC number: 903-139-3 | CAS number: -
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The toxicity of the test substance to the freshwater alga Pseudokirchneriella subcapitata was determined according to OECD 201. After 72 hours the NOEC, the EC10 and the EC50 were determined to be greater than 320 mg/L. In addition study results are available for the other category members, revealing EC50 and EC10 values well above 100 mg/L.
Key value for chemical safety assessment
Additional information
The toxicity of the test substance pentanol, branched and linear (CAS 94624-12-1) to the freshwater alga Pseudokirchneriella subcapitata was determined according to the principles of OECD 201 under GLP conditions (BASF 2011). The aim of the study was to assess the effects on growth rate and yield over a period of 72 hours. After 72 hours the NOEC, the EC10 and the EC50 were determined to be greater than 320 mg/L.
In addition, a read across category approach was done to the other category members.
A publication (Bringmann et al. 1977) is available describing the influence of the read across substance pentan-1-ol on the growth of the freshwater algae Scenedesmus quadricauda. The study was conducted under static conditions. The 8 days EC50 was determined to be 260 mg test item/L. No EC10 value is available from this study.
Furthermore, the toxicity of the surrogate test substance 2-methylbutan-1-ol to the freshwater alga Pseudokirchneriella subcapitata was determined also according to the principles of OECD 201 under GLP conditions (BASF 2011). After 72 hours the NOEC was determined to be 29 mg/L, the ErC10 was determined to be 132 mg/L and the ErC50 was determined to be greater than 353 mg/L. All values based on measured concentrations.
Supplementary the toxicity of the surrogate test substance 3-methylbutan-1-ol Scenedesmus subspicatus (new name: Desmodesmus subspicatus) was determined also according to DIN 38412 part 9 under Non-GLP conditions (BASF 1989). After 72 hours the ErC10 was determined to be 141 mg/L and the EC50 was determined to be greater than 500 mg/L (growth rate) and 493 mg/L (biomass). All values based on nominal concentrations.
In conclusion, the 72h-EC50 and the 72h-EC10 value of the test substance and of the read across category members was determined to be greater than 100 mg/L.
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