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EC number: 217-110-1 | CAS number: 1742-95-6
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
48 hrs aquatic toxicity studies (EPI suite, ECOSAR version 1.1, 2016) were conducted to assess toxic effects of the 4-Amino-1,8-naphthalimide (CAS no 1742-95-6) and the results were predicted. The study was based on the effects of the test compound on the Daphnia magna in a static fresh water system. The predicted data suggests the lethal concentration (LC50) for the 4-Amino-1, 8-naphthalimide (CAS no 1742-95-6) was estimated to be 614.752 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 614.752 mg/L
Additional information
Predicted studies for the 4-Amino-1,8-naphthalimide were reviewed to summarize the following information:
In 48 hrs aquatic toxicity studies (EPI suite, ECOSAR version 1.1, 2016) were conducted to assess toxic effects of the 4-Amino-1, 8-naphthalimide (CAS no 1742-95-6) and the results were predicted. The study was based on the effects of the test compound on the Daphnia magna in a static fresh water system. The predicted data suggests the lethal concentration (LC50) for the 4-Amino-1, 8-naphthalimide (CAS no 1742-95-6) was estimated to be 614.752 mg/L.
Another prediction model for aquatic toxicity (SSS QSAR prediction model, 2016) were conducted to assess toxic effects of the 4-Amino-1, 8-naphthalimide (CAS number: 1742-95-6).The study was conducted on the Daphnia magna in a static fresh water system. The predicted data suggests the effective concentration (EC50) for 4-Amino-1, 8-naphthalimide (CAS number: 1742-95-6) was estimated to be 108.003410339 mg/l on the basis of intoxication.
On the basis of results of prediction report on toxicity to aquatic invertebrates , it can be considered that 4-Amino-1,8-naphthalimide is not likely to be toxic to aquatic invertebrates at environmentally relevant concentrations and can be considered as not hazardous to aquatic biota.
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